By HOWARD BECK

Mike D’Antoni has resigned as head coach of the Knicks, a result of a season-long struggle to find common ground with Carmelo Anthony, the franchise star.

D’Antoni made the decision official in a meeting Wednesday afternoon with James L. Dolan, the Madison Square Garden chairman, and Glen Grunwald, the interim general manager.

Mike Woodson, who joined the coaching staff last summer — and was viewed as the emergency replacement, if necessary — will coach the Knicks on Wednesday night against the Portland Trail Blazers. Woodson previously coached the Atlanta Hawks.

D’Antoni’s decision was first reported by Yahoo Sports. Two of D’Antoni’s assistants, his brother Dan and Phil Weber, are also resigning. Woodson will be assisted by the two holdovers, Kenny Atkinson and Herb Williams.

A person with close ties to Mike D’Antoni said that D’Antoni initiated Wednesday’s meeting with Dolan and that the decision to step down “was absolutely Mike’s.”

Knicks players were said to be stunned and disappointed. Although Anthony has been frustrated by D’Antoni’s system, the vast majority of the locker room supported the coach. He had the strong backing of Amar’e Stoudemire, Tyson Chandler, Jeremy Lin, Jared Jeffries and Landry Fields, the core of the team.

The news also came as a shock to people close to D’Antoni, who apparently reached the decision sometime Tuesday night or Wednesday morning. D’Antoni coached the team at the morning shoot-around in Greenburgh, N.Y.

The Knicks have lost six straight games and eight of their last 10, jeopardizing their playoff standing and erasing the gains made in an 8-1 stretch last month, when Lin revived D’Antoni’s offense.

D’Antoni has been working, unsuccessfully, to get Anthony to mesh his considerable talents with an offensive system predicated on ball movement. Anthony prefers to score in isolation sets — the antithesis of D’Antoni’s approach — and has frequently broken plays to create shots for himself.

The tension between Anthony and D’Antoni — and more broadly, between Anthony and the rest of the team — was undermining the Knicks’ cohesion and morale. Most of the team preferred to keep playing the way they were during the so-called Linsanity streak in February, when Lin was initiating the offense.

D’Antoni came to the conclusion that the continuing tension was hurting both him and Anthony and ultimately sinking the Knicks, according to a person who spoke with D’Antoni on Wednesday. With his contract expiring after the season, D’Antoni decided that it was best to sever ties now and let the Knicks determine the best way to maximize Anthony’s skills.

“He basically said he didn’t see how he could coach them to success the way it was right now,” said the person who spoke to D’Antoni. The person added, “He didn’t want to get beat up for the next two months or see Melo get beat up for the next two months.”

The Knicks have yet to announce the news. D’Antoni did not return a call seeking comment.